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Conidial Melanin of the Human-Pathogenic Fungus Aspergillus fumigatus Disrupts Cell Autonomous Defenses in Amoebae
The human-pathogenic fungus Aspergillus fumigatus is a ubiquitous saprophyte that causes fatal lung infections in immunocompromised individuals. Following inhalation, conidia are ingested by innate immune cells and can arrest phagolysosome maturation. How this virulence trait could have been selecte...
Autores principales: | Ferling, Iuliia, Dunn, Joe Dan, Ferling, Alexander, Soldati, Thierry, Hillmann, Falk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251208/ https://www.ncbi.nlm.nih.gov/pubmed/32457245 http://dx.doi.org/10.1128/mBio.00862-20 |
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