Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance

Neisseria gonorrhoeae is an obligate human pathogen and causative agent of the sexually transmitted infection (STI) gonorrhea. The most predominant and clinically important multidrug efflux system in N. gonorrhoeae is the multiple transferrable resistance (Mtr) pump, which mediates resistance to a n...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyu, Meinan, Moseng, Mitchell A., Reimche, Jennifer L., Holley, Concerta L., Dhulipala, Vijaya, Su, Chih-Chia, Shafer, William M., Yu, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251214/
https://www.ncbi.nlm.nih.gov/pubmed/32457251
http://dx.doi.org/10.1128/mBio.00996-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251214/
https://www.ncbi.nlm.nih.gov/pubmed/32457251
http://dx.doi.org/10.1128/mBio.00996-20

Ejemplares similares