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Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study

INTRODUCTION: Sexual dysfunction is a common problem in patients with chronic kidney disease. Disturbances in sexual function are noticed in early stages of chronic kidney diseases and deteriorate further as renal function declines. This is due to uremic effects, comorbid illness, anemia, hormonal d...

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Autores principales: Jabali, Shakir Saleem, Saleem, Zana Sidiq M., Mohammed, Ayad Ahmad, Mahmood, Newar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251300/
https://www.ncbi.nlm.nih.gov/pubmed/32477507
http://dx.doi.org/10.1016/j.amsu.2020.04.038
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author Jabali, Shakir Saleem
Saleem, Zana Sidiq M.
Mohammed, Ayad Ahmad
Mahmood, Newar M.
author_facet Jabali, Shakir Saleem
Saleem, Zana Sidiq M.
Mohammed, Ayad Ahmad
Mahmood, Newar M.
author_sort Jabali, Shakir Saleem
collection PubMed
description INTRODUCTION: Sexual dysfunction is a common problem in patients with chronic kidney disease. Disturbances in sexual function are noticed in early stages of chronic kidney diseases and deteriorate further as renal function declines. This is due to uremic effects, comorbid illness, anemia, hormonal disturbances, autonomic neuropathy, vascular diseases, hyperparathyroidism, hyperprolactinemia, side effects of medications, and psychosocial factors. PATIENTS AND METHOD: This is a cross-sectional study which included 59 male patients who underwent renal transplantation for more than 6 months. The International Index of Erectile Function (IIEF-5) was adopted in our study to record the erectile function. RESULTS: The mean age was 49.41 years, and the mean number of hemodialysis per month was 5.31. The cause of the chronic kidney disease was diabetes mellitus in 35.59%, glomerulonephritis in 20.34%, and hypertension in 16.95%, other causes were diagnosed in order of decreasing frequency. Most patients developed improvement in the erectile function after transplantation. There was significant correlation with 3 of the elements of the IIFE-5.i.e; penile hardness pre-penetration, Maintaining erection during intercourse, and Difficulty to maintain erection to complete the intercourse (p values 0.015, 0.011, and 0.023) respectively, and the overall improvement after transplantation which showed a p-value of less than 0.031, while there was no significant correlation with Confidence with erection and Satisfaction with intercourse before and after transplantation (p values 0.113 and 0.121) respectively. One of the patients (1.7%) developed severe dysfunction after that. CONCLUSION: ED is common sequel of chronic kidney disease. The etiology is multifactorial and may be worsen by advanced age, presence of diabetes mellitus and prolonged duration of hemodialysis. Renal transplantation has a positive impact on sexual function and lead to improvement of erectile dysfunction. Erectile dysfunction that persists after kidney transplantation is usually attributed to multiple preexisting comorbidities.
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spelling pubmed-72513002020-05-29 Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study Jabali, Shakir Saleem Saleem, Zana Sidiq M. Mohammed, Ayad Ahmad Mahmood, Newar M. Ann Med Surg (Lond) Original Research INTRODUCTION: Sexual dysfunction is a common problem in patients with chronic kidney disease. Disturbances in sexual function are noticed in early stages of chronic kidney diseases and deteriorate further as renal function declines. This is due to uremic effects, comorbid illness, anemia, hormonal disturbances, autonomic neuropathy, vascular diseases, hyperparathyroidism, hyperprolactinemia, side effects of medications, and psychosocial factors. PATIENTS AND METHOD: This is a cross-sectional study which included 59 male patients who underwent renal transplantation for more than 6 months. The International Index of Erectile Function (IIEF-5) was adopted in our study to record the erectile function. RESULTS: The mean age was 49.41 years, and the mean number of hemodialysis per month was 5.31. The cause of the chronic kidney disease was diabetes mellitus in 35.59%, glomerulonephritis in 20.34%, and hypertension in 16.95%, other causes were diagnosed in order of decreasing frequency. Most patients developed improvement in the erectile function after transplantation. There was significant correlation with 3 of the elements of the IIFE-5.i.e; penile hardness pre-penetration, Maintaining erection during intercourse, and Difficulty to maintain erection to complete the intercourse (p values 0.015, 0.011, and 0.023) respectively, and the overall improvement after transplantation which showed a p-value of less than 0.031, while there was no significant correlation with Confidence with erection and Satisfaction with intercourse before and after transplantation (p values 0.113 and 0.121) respectively. One of the patients (1.7%) developed severe dysfunction after that. CONCLUSION: ED is common sequel of chronic kidney disease. The etiology is multifactorial and may be worsen by advanced age, presence of diabetes mellitus and prolonged duration of hemodialysis. Renal transplantation has a positive impact on sexual function and lead to improvement of erectile dysfunction. Erectile dysfunction that persists after kidney transplantation is usually attributed to multiple preexisting comorbidities. Elsevier 2020-05-16 /pmc/articles/PMC7251300/ /pubmed/32477507 http://dx.doi.org/10.1016/j.amsu.2020.04.038 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research
Jabali, Shakir Saleem
Saleem, Zana Sidiq M.
Mohammed, Ayad Ahmad
Mahmood, Newar M.
Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study
title Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study
title_full Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study
title_fullStr Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study
title_full_unstemmed Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study
title_short Erectile dysfunction pre and post kidney transplant recipients in Duhok city; cross sectional study
title_sort erectile dysfunction pre and post kidney transplant recipients in duhok city; cross sectional study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251300/
https://www.ncbi.nlm.nih.gov/pubmed/32477507
http://dx.doi.org/10.1016/j.amsu.2020.04.038
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