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Medication-Related Quality of Life in Thai Epilepsy Patients
BACKGROUND AND PURPOSE: This study aimed to assess medication-related quality of life in Thai patients with epilepsy. The second objective was to evaluate the associations between the medication therapy-related quality of life and patient characteristics. METHODS: This was a cross-sectional study. A...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Epilepsy Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251341/ https://www.ncbi.nlm.nih.gov/pubmed/32509550 http://dx.doi.org/10.14581/jer.19016 |
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author | Sakthong, Phantipa Suriyapakorn, Bavornpat |
author_facet | Sakthong, Phantipa Suriyapakorn, Bavornpat |
author_sort | Sakthong, Phantipa |
collection | PubMed |
description | BACKGROUND AND PURPOSE: This study aimed to assess medication-related quality of life in Thai patients with epilepsy. The second objective was to evaluate the associations between the medication therapy-related quality of life and patient characteristics. METHODS: This was a cross-sectional study. A convenience sample of 173 outpatients with epilepsy was recruited from a university hospital in Bangkok, Thailand. Inclusion criteria were aged 18 or over who were continuously taking an epileptic drug for at least 3 months, understanding Thai language, and willing to participate in the study. The Patient-Reported Outcomes Measure of Pharmaceutical Therapy for Quality of Life (PROMPT-QoL) was utilized to measure the medication therapy-related quality of life. Pearson’s correlation coefficients and stepwise multiple linear regressions were employed to assess the relationships between eight PROMPT-QoL domain scores and patient demographic and clinical characteristics. RESULTS: Mean age was 36.4±9.5 years and approximately 57% were female. Among eight domains of the PROMPT-QoL, the therapeutic relationships with health care providers and psychological impacts of medication use domains yielded the highest (77.9) and lowest (61.9) mean scores, respectively. Seven out of eight PROMPT-QoL domain scores were considered as moderate-to-good. Age, gender, duration of epilepsy, seizure frequency, and treatment preference were significantly associated with PROMPT-QoL domain scores in multivariate linear regression analyses. CONCLUSIONS: This study showed that Thai patients with epilepsy had moderate-to-good medication therapy-related quality of life. Healthcare providers should pay more attention to patients’ psychological impacts of antiepileptic drugs and those with characteristics related to lower medication therapy-related quality of life. |
format | Online Article Text |
id | pubmed-7251341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Epilepsy Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-72513412020-06-05 Medication-Related Quality of Life in Thai Epilepsy Patients Sakthong, Phantipa Suriyapakorn, Bavornpat J Epilepsy Res Original Article BACKGROUND AND PURPOSE: This study aimed to assess medication-related quality of life in Thai patients with epilepsy. The second objective was to evaluate the associations between the medication therapy-related quality of life and patient characteristics. METHODS: This was a cross-sectional study. A convenience sample of 173 outpatients with epilepsy was recruited from a university hospital in Bangkok, Thailand. Inclusion criteria were aged 18 or over who were continuously taking an epileptic drug for at least 3 months, understanding Thai language, and willing to participate in the study. The Patient-Reported Outcomes Measure of Pharmaceutical Therapy for Quality of Life (PROMPT-QoL) was utilized to measure the medication therapy-related quality of life. Pearson’s correlation coefficients and stepwise multiple linear regressions were employed to assess the relationships between eight PROMPT-QoL domain scores and patient demographic and clinical characteristics. RESULTS: Mean age was 36.4±9.5 years and approximately 57% were female. Among eight domains of the PROMPT-QoL, the therapeutic relationships with health care providers and psychological impacts of medication use domains yielded the highest (77.9) and lowest (61.9) mean scores, respectively. Seven out of eight PROMPT-QoL domain scores were considered as moderate-to-good. Age, gender, duration of epilepsy, seizure frequency, and treatment preference were significantly associated with PROMPT-QoL domain scores in multivariate linear regression analyses. CONCLUSIONS: This study showed that Thai patients with epilepsy had moderate-to-good medication therapy-related quality of life. Healthcare providers should pay more attention to patients’ psychological impacts of antiepileptic drugs and those with characteristics related to lower medication therapy-related quality of life. Korean Epilepsy Society 2019-12-31 /pmc/articles/PMC7251341/ /pubmed/32509550 http://dx.doi.org/10.14581/jer.19016 Text en Copyright © 2019 Korean Epilepsy Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Sakthong, Phantipa Suriyapakorn, Bavornpat Medication-Related Quality of Life in Thai Epilepsy Patients |
title | Medication-Related Quality of Life in Thai Epilepsy Patients |
title_full | Medication-Related Quality of Life in Thai Epilepsy Patients |
title_fullStr | Medication-Related Quality of Life in Thai Epilepsy Patients |
title_full_unstemmed | Medication-Related Quality of Life in Thai Epilepsy Patients |
title_short | Medication-Related Quality of Life in Thai Epilepsy Patients |
title_sort | medication-related quality of life in thai epilepsy patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251341/ https://www.ncbi.nlm.nih.gov/pubmed/32509550 http://dx.doi.org/10.14581/jer.19016 |
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