Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses

BACKGROUND: Pancreatic patient–derived organoids (PDOs) are a well-established model for studying pancreatic ductal adenocarcinoma (PDAC) carcinogenesis and are potential predictors of clinical responses to chemotherapy. Oncolytic virotherapy is envisioned as a novel treatment modality for pancreati...

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Detalles Bibliográficos
Autores principales: Raimondi, Giulia, Mato-Berciano, Ana, Pascual-Sabater, Silvia, Rovira-Rigau, Maria, Cuatrecasas, Miriam, Fondevila, Constantino, Sánchez-Cabús, Santiago, Begthel, Harry, Boj, Sylvia F., Clevers, Hans, Fillat, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251378/
https://www.ncbi.nlm.nih.gov/pubmed/32460166
http://dx.doi.org/10.1016/j.ebiom.2020.102786

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