Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase

Following traumatic insult and associated pathogen infection, innate immunity is activated during the perioperative period, especially the NLRP3 inflammasome in macrophages. The neuroendocrine response is also rapidly activated to regulate excessive inflammation; however, the molecular mechanisms ar...

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Detalles Bibliográficos
Autores principales: Wu, Ling, Zhou, Chengfu, Wu, Jianfeng, Chen, Shikun, Tian, Zedan, Du, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251469/
https://www.ncbi.nlm.nih.gov/pubmed/32508525
http://dx.doi.org/10.1155/2020/6959741

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