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Intranasal Delivery of miR-155-5p Antagomir Alleviates Acute Seizures Likely by Inhibiting Hippocampal Inflammation

INTRODUCTION: To confront the resistance to existing antiepileptic drugs, studies have gradually begun to investigate alternative pathologies distinct from the traditional treatments that overwhelmingly target ion channels. Microglia activation is the first inflammatory response in the brain, in whi...

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Detalles Bibliográficos
Autores principales: Zhou, Xu, Chen, Jun, Tao, Hua, Cai, Yujie, Huang, Lidan, Zhou, Haihong, Chen, Yanyan, Cui, Lili, Zhong, Wangtao, Li, Keshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251485/
https://www.ncbi.nlm.nih.gov/pubmed/32547033
http://dx.doi.org/10.2147/NDT.S247677