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Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models

This paper aims to study the impact of using an educational strategy on reducing the efforts needed to control respiratory transmitted infections represented by SIR models, taking into account heterogeneity in contacts between infected and non-infected individuals. Therefore, a new incidence functio...

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Autor principal: Safan, Muntaser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251563/
https://www.ncbi.nlm.nih.gov/pubmed/32501395
http://dx.doi.org/10.1186/s13662-020-02708-8
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author Safan, Muntaser
author_facet Safan, Muntaser
author_sort Safan, Muntaser
collection PubMed
description This paper aims to study the impact of using an educational strategy on reducing the efforts needed to control respiratory transmitted infections represented by SIR models, taking into account heterogeneity in contacts between infected and non-infected individuals. Therefore, a new incidence function, in which the difference in contact time activity between infected and non-infected individuals is taken into account, is formulated. Equilibrium and stability analyses of the model have been carried out. The model has been extended to include the effect of herd immunity and the analysis showed that the higher the percent reduction [Formula: see text] in the contact-activity time of infected individuals is, the lower the critical vaccination coverage level [Formula: see text] required to eliminate the infection is, and therefore, the lower the infection’s minimum elimination effort is. Another extension of the basic model to include a control strategy based on treating infected individuals at rate α with a maximum capacity treatment [Formula: see text] has been considered. The equilibrium analysis showed the existence of multiple subcritical and supercritical endemic equilibria, while the stability analysis showed that the model exhibits a Hopf bifurcation. Simulations showed that the higher the maximum treatment capacity [Formula: see text] is, the lower the value of the critical reduction in infected individuals’ time activity [Formula: see text] , at which a Hopf bifurcation is generated, is. Simulations with parameter values corresponding to the case of influenza A have been carried out.
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spelling pubmed-72515632020-05-27 Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models Safan, Muntaser Adv Differ Equ Research This paper aims to study the impact of using an educational strategy on reducing the efforts needed to control respiratory transmitted infections represented by SIR models, taking into account heterogeneity in contacts between infected and non-infected individuals. Therefore, a new incidence function, in which the difference in contact time activity between infected and non-infected individuals is taken into account, is formulated. Equilibrium and stability analyses of the model have been carried out. The model has been extended to include the effect of herd immunity and the analysis showed that the higher the percent reduction [Formula: see text] in the contact-activity time of infected individuals is, the lower the critical vaccination coverage level [Formula: see text] required to eliminate the infection is, and therefore, the lower the infection’s minimum elimination effort is. Another extension of the basic model to include a control strategy based on treating infected individuals at rate α with a maximum capacity treatment [Formula: see text] has been considered. The equilibrium analysis showed the existence of multiple subcritical and supercritical endemic equilibria, while the stability analysis showed that the model exhibits a Hopf bifurcation. Simulations showed that the higher the maximum treatment capacity [Formula: see text] is, the lower the value of the critical reduction in infected individuals’ time activity [Formula: see text] , at which a Hopf bifurcation is generated, is. Simulations with parameter values corresponding to the case of influenza A have been carried out. Springer International Publishing 2020-05-27 2020 /pmc/articles/PMC7251563/ /pubmed/32501395 http://dx.doi.org/10.1186/s13662-020-02708-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research
Safan, Muntaser
Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models
title Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models
title_full Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models
title_fullStr Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models
title_full_unstemmed Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models
title_short Impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in SIR models
title_sort impact of reduction in contact time activity of infected individuals on the dynamics and control of directly transmitted respiratory infections in sir models
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251563/
https://www.ncbi.nlm.nih.gov/pubmed/32501395
http://dx.doi.org/10.1186/s13662-020-02708-8
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