Less NMDA Receptor Binding in Dorsolateral Prefrontal Cortex and Anterior Cingulate Cortex Associated With Reported Early-Life Adversity but Not Suicide

BACKGROUND: Glutamate is an excitatory neurotransmitter binding to 3 classes of receptors, including the N-methyl, D-aspartate (NMDA) receptor. NMDA receptor binding is lower in major depression disorder and suicide. NMDA receptor blocking with ketamine can have antidepressant and anti-suicide effec...

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Detalles Bibliográficos
Autores principales: Underwood, Mark D, Bakalian, Mihran J, Johnson, Virginia L, Kassir, Suham A, Ellis, Steven P, Mann, J John, Arango, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251634/
https://www.ncbi.nlm.nih.gov/pubmed/32060512
http://dx.doi.org/10.1093/ijnp/pyaa009

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