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Polydatin improves osteogenic differentiation of human bone mesenchymal stem cells by stimulating TAZ expression via BMP2-Wnt/β-catenin signaling pathway

OBJECTIVES: Polydatin (PD), extracted from Polygonum cuspidatum, has shown potential therapeutic applications due to its antiosteoporotic and anti-inflammatory activities. Our previous study suggested that PD promotes the osteogenesis of human bone marrow stromal cells (hBMSCs) via the BMP2-Wnt/β-ca...

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Detalles Bibliográficos
Autores principales: Shen, Ying-Shan, Chen, Xiao-Jun, Wuri, Sha-Na, Yang, Fan, Pang, Feng-Xiang, Xu, Liang-Liang, He, Wei, Wei, Qiu-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251742/
https://www.ncbi.nlm.nih.gov/pubmed/32460844
http://dx.doi.org/10.1186/s13287-020-01705-8