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SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation

BACKGROUND: It has been confirmed that NF-κB p65 signaling pathway is involved in the regulation of alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome (ARDS). Whether SN50, a NF-κB cell permeable inhibitor, could attenuate alveolar hypercoagulation and fibri...

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Detalles Bibliográficos
Autores principales: Wu, Yanqi, Wang, Yahui, Liu, Bo, Cheng, Yumei, Qian, Hong, Yang, Huilin, Li, Xiang, Yang, Guixia, Zheng, Xinghao, Shen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251840/
https://www.ncbi.nlm.nih.gov/pubmed/32460750
http://dx.doi.org/10.1186/s12931-020-01372-6