Cargando…

Transplantation of bone marrow mesenchymal stem cells improves cognitive deficits and alleviates neuropathology in animal models of Alzheimer’s disease: a meta-analytic review on potential mechanisms

BACKGROUND: Alzheimer’s disease is a neurodegenerative disorder. Therapeutically, a transplantation of bone marrow mesenchymal stem cells (BMMSCs) can play a beneficial role in animal models of Alzheimer’s disease. However, the relevant mechanism remains to be fully elucidated. MAIN BODY: Subsequent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Chuan, Lu, Yalan, Wang, Kewei, Bai, Lin, Shi, Guiying, Huang, Yiying, Li, Yongning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251864/ https://www.ncbi.nlm.nih.gov/pubmed/32460886 http://dx.doi.org/10.1186/s40035-020-00199-x

Ejemplares similares

Novel Balance Mechanism Participates in Stem Cell Therapy to Alleviate Neuropathology and Cognitive Impairment in Animal Models with Alzheimer’s Disease
por: Qin, Chuan, et al.
Publicado: (2021)

The functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer’s disease: crosstalk between autophagy and apoptosis
por: Qin, Chuan, et al.
Publicado: (2022)

Functional Mechanism of Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Animal Models with Alzheimer’s Disease: Inhibition of Neuroinflammation
por: Qin, Chuan, et al.
Publicado: (2021)

A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches
por: Lu, Yalan, et al.
Publicado: (2022)

Nano‐Brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits
por: Zhang, Qian, et al.
Publicado: (2023)

Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model
por: Luo, Kaixuan, et al.
Publicado: (2022)

Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model
por: Xu, Jiqing, et al.
Publicado: (2016)

Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is dependent on passage number
por: Rossignol, Julien, et al.
Publicado: (2015)

Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology
por: Liu, Sen, et al.
Publicado: (2022)

ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer’s disease models
por: Zhao, Yuanyuan, et al.
Publicado: (2022)

Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer’s disease mouse model
por: Flores, Joseph, et al.
Publicado: (2018)

Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice
por: Xu, Zhipeng, et al.
Publicado: (2014)

Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease
por: Wu, Wenjuan, et al.
Publicado: (2019)

Allogeneic Adipose-Derived Mesenchymal Stem Cell Transplantation Alleviates Atherosclerotic Plaque by Inhibiting Ox-LDL Uptake, Inflammatory Reaction and Endothelial Damage in Rabbits
por: Li, Yanhong, et al.
Publicado: (2023)

Effects of mesenchymal stem cells transplantation on cognitive deficits in animal models of Alzheimer’s disease: A systematic review and meta‐analysis
por: Ge, Meiling, et al.
Publicado: (2018)

Neuropathology of Animal Prion Diseases
por: Orge, Leonor, et al.
Publicado: (2021)

The neuropathological diagnosis of Alzheimer’s disease
por: DeTure, Michael A., et al.
Publicado: (2019)

Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice
por: Chang, Yanmin, et al.
Publicado: (2021)

Gallic and ascorbic acids supplementation alleviate cognitive deficits and neuropathological damage exerted by cadmium chloride in Wistar rats
por: Adebiyi, Olamide, et al.
Publicado: (2022)

Static and Dynamic Cognitive Reserve Proxy Measures: Interactions with Alzheimer’s Disease Neuropathology and Cognition
por: Malek-Ahmadi, Michael, et al.
Publicado: (2017)

Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer’s disease
por: Wang, Qi, et al.
Publicado: (2021)

Corrigendum: Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice
por: Chang, Yanmin, et al.
Publicado: (2021)

Effectiveness and mechanisms of adipose-derived stem cell therapy in animal models of Parkinson’s disease: a systematic review and meta-analysis
por: Li, Keya, et al.
Publicado: (2021)

Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development
por: Rabinovici, Gil D., et al.
Publicado: (2016)

Neuropathology of transgenic HD animal models
por: Li, Xiaojiang, et al.
Publicado: (2012)

Epigenetic Modifications in Alzheimer’s Neuropathology and Therapeutics
por: Esposito, Michelle, et al.
Publicado: (2019)

Illustrated Neuropathologic Diagnosis of Alzheimer’s Disease
por: Doher, Nicholas, et al.
Publicado: (2023)

Transplantation of bone marrow-derived mesenchymal stem cells expressing elastin alleviates pelvic floor dysfunction
por: Jin, Minfei, et al.
Publicado: (2016)

Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model
por: Costa-Marques, Luís, et al.
Publicado: (2019)

Transplanted Bone Marrow Mesenchymal Stem Cells Improve Memory in Rat Models of Alzheimer's Disease
por: Babaei, Parvin, et al.
Publicado: (2012)

Microglia in Alzheimer Brain: A Neuropathological Perspective
por: Mrak, Robert E.
Publicado: (2012)

Alzheimer disease neuropathology: understanding autonomic dysfunction
por: Engelhardt, Eliasz, et al.
Publicado: (2008)

Neuropathological Mechanisms Associated with Pesticides in Alzheimer’s Disease
por: Tang, Bor Luen
Publicado: (2020)

Progranulin mutations in clinical and neuropathological Alzheimer's disease
por: Vardarajan, Badri N., et al.
Publicado: (2022)

Cognitive resilience and severe Alzheimer’s disease neuropathology
por: Ahangari, Narges, et al.
Publicado: (2023)

Cognitive deficits and Alzheimer-like neuropathological impairments during adolescence in a rat model of type 2 diabetes mellitus
por: Jin, Li, et al.
Publicado: (2018)

Lipids and lipoproteins may play a role in the neuropathology of Alzheimer’s disease
por: Akyol, Omer, et al.
Publicado: (2023)

Trilobatin Alleviates Cognitive Deficits and Pathologies in an Alzheimer's Disease Mouse Model
por: Ding, Jiuyang, et al.
Publicado: (2021)

Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease
por: Bian, Yaqi, et al.
Publicado: (2021)

Lamotrigine protects against cognitive deficits, synapse and nerve cell damage, and hallmark neuropathologies in a mouse model of Alzheimer’s disease
por: Fu, Xin-Xin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m7o8v7tef039jocmq1n1nl59b3