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Three-dimensional culture of MSCs produces exosomes with improved yield and enhanced therapeutic efficacy for cisplatin-induced acute kidney injury

BACKGROUND: Exosomes derived from mesenchymal stem cells (MSC-exos) have been demonstrated with great potential in the treatment of multiple human diseases including acute kidney injury (AKI) by virtue of their intrinsic cargoes. However, there are major challenges of low yield and the lack of an es...

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Detalles Bibliográficos
Autores principales:	Cao, Jingyuan, Wang, Bin, Tang, Taotao, Lv, Linli, Ding, Zhaoying, Li, Zuolin, Hu, Ruoyu, Wei, Qing, Shen, Anran, Fu, Yuqi, Liu, Bicheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251891/ https://www.ncbi.nlm.nih.gov/pubmed/32460853 http://dx.doi.org/10.1186/s13287-020-01719-2

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