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CAMKK2-CAMK4 signaling regulates transferrin trafficking, turnover, and iron homeostasis
BACKGROUND: Circulatory iron is a hazardous biometal. Therefore, iron is transported in a redox-safe state by a serum glycoprotein - transferrin (TF). Different organs acquire iron from the systemic circulation through a tightly regulated mechanism at the blood-tissue interface which involves recept...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251913/ https://www.ncbi.nlm.nih.gov/pubmed/32460794 http://dx.doi.org/10.1186/s12964-020-00575-0 |