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Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view

Now COVID-19 is causing a severe public health emergency and the mortality is rapidly increasing all over the world. In the current pandemic era, although there have been many efforts to diagnose a number of patients with symptoms or close contacts, there is no definite guideline for the initial the...

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Autores principales: Kronbichler, Andreas, Effenberger, Maria, Eisenhut, Michael, Lee, Keum Hwa, Shin, Jae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252097/
https://www.ncbi.nlm.nih.gov/pubmed/32376397
http://dx.doi.org/10.1016/j.autrev.2020.102570
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author Kronbichler, Andreas
Effenberger, Maria
Eisenhut, Michael
Lee, Keum Hwa
Shin, Jae Il
author_facet Kronbichler, Andreas
Effenberger, Maria
Eisenhut, Michael
Lee, Keum Hwa
Shin, Jae Il
author_sort Kronbichler, Andreas
collection PubMed
description Now COVID-19 is causing a severe public health emergency and the mortality is rapidly increasing all over the world. In the current pandemic era, although there have been many efforts to diagnose a number of patients with symptoms or close contacts, there is no definite guideline for the initial therapeutic approach for them and therefore, many patients have been dying due to a hyperinflammatory immunological reaction labeled as “cytokine storm”. Severe patients are hospitalized and the treatment is done, though they have not been established yet. Currently, however, no treatment is provided for those who are isolated at home or shelter until they get severe symptoms, which will increase the harms to the patients. In this review, we discuss some important points dedicated to the management of patients with COVID-19, which should help reducing morbidity and mortality. In this era, we suggest 7 recommendations to rescue the patients and to reduce the morbidity and mortality due to COVID-19 based on the immunological point of view.
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spelling pubmed-72520972020-05-28 Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view Kronbichler, Andreas Effenberger, Maria Eisenhut, Michael Lee, Keum Hwa Shin, Jae Il Autoimmun Rev Article Now COVID-19 is causing a severe public health emergency and the mortality is rapidly increasing all over the world. In the current pandemic era, although there have been many efforts to diagnose a number of patients with symptoms or close contacts, there is no definite guideline for the initial therapeutic approach for them and therefore, many patients have been dying due to a hyperinflammatory immunological reaction labeled as “cytokine storm”. Severe patients are hospitalized and the treatment is done, though they have not been established yet. Currently, however, no treatment is provided for those who are isolated at home or shelter until they get severe symptoms, which will increase the harms to the patients. In this review, we discuss some important points dedicated to the management of patients with COVID-19, which should help reducing morbidity and mortality. In this era, we suggest 7 recommendations to rescue the patients and to reduce the morbidity and mortality due to COVID-19 based on the immunological point of view. Elsevier B.V. 2020-07 2020-05-03 /pmc/articles/PMC7252097/ /pubmed/32376397 http://dx.doi.org/10.1016/j.autrev.2020.102570 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kronbichler, Andreas
Effenberger, Maria
Eisenhut, Michael
Lee, Keum Hwa
Shin, Jae Il
Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view
title Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view
title_full Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view
title_fullStr Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view
title_full_unstemmed Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view
title_short Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view
title_sort seven recommendations to rescue the patients and reduce the mortality from covid-19 infection: an immunological point of view
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252097/
https://www.ncbi.nlm.nih.gov/pubmed/32376397
http://dx.doi.org/10.1016/j.autrev.2020.102570
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