Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol

Cefiderocol is a novel catechol siderophore cephalosporin antibiotic developed to treat resistant gram-negative infections. We describe its successful use as rescue therapy, combined with surgical debridement, to treat a patient with osteomyelitis due to extensively drug-resistant Acinetobacter baum...

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Detalles Bibliográficos
Autores principales: Dagher, Michael, Ruffin, Felicia, Marshall, Steven, Taracila, Magdalena, Bonomo, Robert A, Reilly, Rachel, Fowler, Vance G, Thaden, Joshua T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252278/
https://www.ncbi.nlm.nih.gov/pubmed/32494581
http://dx.doi.org/10.1093/ofid/ofaa150
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author Dagher, Michael
Ruffin, Felicia
Marshall, Steven
Taracila, Magdalena
Bonomo, Robert A
Reilly, Rachel
Fowler, Vance G
Thaden, Joshua T
author_facet Dagher, Michael
Ruffin, Felicia
Marshall, Steven
Taracila, Magdalena
Bonomo, Robert A
Reilly, Rachel
Fowler, Vance G
Thaden, Joshua T
author_sort Dagher, Michael
collection PubMed
description Cefiderocol is a novel catechol siderophore cephalosporin antibiotic developed to treat resistant gram-negative infections. We describe its successful use as rescue therapy, combined with surgical debridement, to treat a patient with osteomyelitis due to extensively drug-resistant Acinetobacter baumannii. Bacterial whole-genome sequencing identified the strain and antibiotic resistance determinants.
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spelling pubmed-72522782020-06-02 Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol Dagher, Michael Ruffin, Felicia Marshall, Steven Taracila, Magdalena Bonomo, Robert A Reilly, Rachel Fowler, Vance G Thaden, Joshua T Open Forum Infect Dis Brief Report Cefiderocol is a novel catechol siderophore cephalosporin antibiotic developed to treat resistant gram-negative infections. We describe its successful use as rescue therapy, combined with surgical debridement, to treat a patient with osteomyelitis due to extensively drug-resistant Acinetobacter baumannii. Bacterial whole-genome sequencing identified the strain and antibiotic resistance determinants. Oxford University Press 2020-05-05 /pmc/articles/PMC7252278/ /pubmed/32494581 http://dx.doi.org/10.1093/ofid/ofaa150 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Dagher, Michael
Ruffin, Felicia
Marshall, Steven
Taracila, Magdalena
Bonomo, Robert A
Reilly, Rachel
Fowler, Vance G
Thaden, Joshua T
Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol
title Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol
title_full Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol
title_fullStr Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol
title_full_unstemmed Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol
title_short Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol
title_sort case report: successful rescue therapy of extensively drug-resistant acinetobacter baumannii osteomyelitis with cefiderocol
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252278/
https://www.ncbi.nlm.nih.gov/pubmed/32494581
http://dx.doi.org/10.1093/ofid/ofaa150
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