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Inhibiting the NF-κB pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer

Optimizing the currently available treatment options for pancreatic cancer (PC) is a priority. Cabazitaxel (CTX), a semisynthetic taxane, is mainly used for treating patients with PC who are resistant to paclitaxel (PTX) or docetaxel, due its poor affinity for P-glycoprotein. However, there are only...

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Detalles Bibliográficos
Autores principales:	Li, Zequn, Xuan, Zefeng, Chen, Jian, Song, Wenfeng, Zhang, Shiyu, Jin, Cheng, Zhou, Mengqiao, Zheng, Shusen, Song, Penghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252454/ https://www.ncbi.nlm.nih.gov/pubmed/32377719 http://dx.doi.org/10.3892/ijo.2020.5053

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