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Intratracheal aerosolization of viral vectors to newborn pig airways
Gene therapy for airway diseases requires efficient delivery of nucleic acids to the airways. In small animal models, gene delivery reagents are commonly delivered as a bolus dose. However, large animal models are often more relevant for the transition from preclinical studies to human trials. Aeros...
Autores principales: | Cooney, Ashley L, Sinn, Patrick L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252491/ https://www.ncbi.nlm.nih.gov/pubmed/32141776 http://dx.doi.org/10.2144/btn-2019-0150 |
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