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CRISPRi-mediated functional analysis of lung disease-associated loci at non-coding regions
Genome-wide association studies have identified lung disease-associated loci; however, the functions of such loci are not well understood in part because the majority of such loci are located at non-coding regions. Hi-C, ChIP-seq and eQTL data predict potential roles (e.g. enhancer) of such loci; ho...
Autores principales: | Stuart, William D, Guo, Minzhe, Fink-Baldauf, Iris M, Coleman, Alan M, Clancy, John P, Mall, Marcus A, Lim, Foong-Yen, Brewington, John J, Maeda, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252574/ https://www.ncbi.nlm.nih.gov/pubmed/32500120 http://dx.doi.org/10.1093/nargab/lqaa036 |
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