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Controlling the SARS-CoV-2 Spike Glycoprotein Conformation

The coronavirus (CoV) viral host cell fusion spike (S) protein is the primary immunogenic target for virus neutralization and the current focus of many vaccine design efforts. The highly flexible S-protein, with its mobile domains, presents a moving target to the immune system. Here, to better under...

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Detalles Bibliográficos
Autores principales: Henderson, Rory, Edwards, Robert J, Mansouri, Katayoun, Janowska, Katarzyna, Stalls, Victoria, Gobeil, Sophie, Kopp, Megan, Hsu, Allen, Borgnia, Mario, Parks, Rob, Haynes, Barton F., Acharya, Priyamvada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252579/
https://www.ncbi.nlm.nih.gov/pubmed/32511343
http://dx.doi.org/10.1101/2020.05.18.102087