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Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge

Neurocardiogenic syncope is the most frequent cause of syncope in the general population. Many years have been spent on determining an effective treatment for this condition. Conventional treatment usually follows a tiered approach for neurocardiogenic syncope, as follows: first, lifestyle modificat...

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Detalles Bibliográficos
Autores principales: Gampa, Amulya, Upadhyay, Gaurav a.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MediaSphere Medical 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252686/
https://www.ncbi.nlm.nih.gov/pubmed/32477815
http://dx.doi.org/10.19102/icrm.2018.090702
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author Gampa, Amulya
Upadhyay, Gaurav a.
author_facet Gampa, Amulya
Upadhyay, Gaurav a.
author_sort Gampa, Amulya
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description Neurocardiogenic syncope is the most frequent cause of syncope in the general population. Many years have been spent on determining an effective treatment for this condition. Conventional treatment usually follows a tiered approach for neurocardiogenic syncope, as follows: first, lifestyle modification, including increased fluid intake and the introduction of physical counterpressure maneuvers, is tried; then the use of targeted pharmacologic therapy, particularly agents that support blood pressure or that drive blood pressure is attempted; and, finally, pacemaker implantation in patients with a predominant cardioinhibitory component to their syncopal episodes is performed. More recently, autonomic modulation with cardiac ganglion ablation has emerged as a promising treatment modality for patients refractory to traditional approaches. In this review, we sought to summarize the existing therapies for neurocardiogenic syncope and explore the latest research on new modalities of treatment.
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spelling pubmed-72526862020-05-28 Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge Gampa, Amulya Upadhyay, Gaurav a. J Innov Card Rhythm Manag Research Review Neurocardiogenic syncope is the most frequent cause of syncope in the general population. Many years have been spent on determining an effective treatment for this condition. Conventional treatment usually follows a tiered approach for neurocardiogenic syncope, as follows: first, lifestyle modification, including increased fluid intake and the introduction of physical counterpressure maneuvers, is tried; then the use of targeted pharmacologic therapy, particularly agents that support blood pressure or that drive blood pressure is attempted; and, finally, pacemaker implantation in patients with a predominant cardioinhibitory component to their syncopal episodes is performed. More recently, autonomic modulation with cardiac ganglion ablation has emerged as a promising treatment modality for patients refractory to traditional approaches. In this review, we sought to summarize the existing therapies for neurocardiogenic syncope and explore the latest research on new modalities of treatment. MediaSphere Medical 2018-07-15 /pmc/articles/PMC7252686/ /pubmed/32477815 http://dx.doi.org/10.19102/icrm.2018.090702 Text en Copyright: © 2018 Innovations in Cardiac Rhythm Management http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Review
Gampa, Amulya
Upadhyay, Gaurav a.
Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge
title Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge
title_full Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge
title_fullStr Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge
title_full_unstemmed Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge
title_short Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge
title_sort treatment of neurocardiogenic syncope: from conservative to cutting-edge
topic Research Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252686/
https://www.ncbi.nlm.nih.gov/pubmed/32477815
http://dx.doi.org/10.19102/icrm.2018.090702
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