Cargando…
Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs
Atrial fibrillation (AF) is often treated with antiarrhythmic drugs (AADs) or catheter ablation. In a unique subset of patients, AF can convert to atrial flutter (AFL) after the initiation of an AAD. It has previously been shown that, in this subset of patients, cavotricuspid isthmus (CTI) ablation...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MediaSphere Medical
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252707/ https://www.ncbi.nlm.nih.gov/pubmed/32477703 http://dx.doi.org/10.19102/icrm.2019.101005 |
_version_ | 1783539201134821376 |
---|---|
author | Riad, Fady S. Waldo, Albert L. |
author_facet | Riad, Fady S. Waldo, Albert L. |
author_sort | Riad, Fady S. |
collection | PubMed |
description | Atrial fibrillation (AF) is often treated with antiarrhythmic drugs (AADs) or catheter ablation. In a unique subset of patients, AF can convert to atrial flutter (AFL) after the initiation of an AAD. It has previously been shown that, in this subset of patients, cavotricuspid isthmus (CTI) ablation followed by the continuation of the AAD regimen has an unusually high rate of successfully maintaining sinus rhythm. This is an underrecognized approach toward rhythm management in such patients. However, the reason(s) for such a high degree of efficacy with this hybrid therapeutic approach are unclear. We suggest that conversion from AF to AFL selects for a group of patients in whom AF is particularly responsive to the effects of the AAD. Since CTI ablation is essentially curative of AFL, the combination of both techniques results in a high efficacy of sinus rhythm maintenance. Further investigation is required to confirm these hypotheses. |
format | Online Article Text |
id | pubmed-7252707 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MediaSphere Medical |
record_format | MEDLINE/PubMed |
spelling | pubmed-72527072020-05-28 Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs Riad, Fady S. Waldo, Albert L. J Innov Card Rhythm Manag Research Review Atrial fibrillation (AF) is often treated with antiarrhythmic drugs (AADs) or catheter ablation. In a unique subset of patients, AF can convert to atrial flutter (AFL) after the initiation of an AAD. It has previously been shown that, in this subset of patients, cavotricuspid isthmus (CTI) ablation followed by the continuation of the AAD regimen has an unusually high rate of successfully maintaining sinus rhythm. This is an underrecognized approach toward rhythm management in such patients. However, the reason(s) for such a high degree of efficacy with this hybrid therapeutic approach are unclear. We suggest that conversion from AF to AFL selects for a group of patients in whom AF is particularly responsive to the effects of the AAD. Since CTI ablation is essentially curative of AFL, the combination of both techniques results in a high efficacy of sinus rhythm maintenance. Further investigation is required to confirm these hypotheses. MediaSphere Medical 2019-10-15 /pmc/articles/PMC7252707/ /pubmed/32477703 http://dx.doi.org/10.19102/icrm.2019.101005 Text en Copyright: © 2019 Innovations in Cardiac Rhythm Management http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Review Riad, Fady S. Waldo, Albert L. Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs |
title | Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs |
title_full | Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs |
title_fullStr | Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs |
title_full_unstemmed | Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs |
title_short | Revisiting an Underrecognized Strategy for Rhythm Management: Hybrid Therapy for Patients who Convert from Atrial Fibrillation to Flutter on Antiarrhythmic Drugs |
title_sort | revisiting an underrecognized strategy for rhythm management: hybrid therapy for patients who convert from atrial fibrillation to flutter on antiarrhythmic drugs |
topic | Research Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252707/ https://www.ncbi.nlm.nih.gov/pubmed/32477703 http://dx.doi.org/10.19102/icrm.2019.101005 |
work_keys_str_mv | AT riadfadys revisitinganunderrecognizedstrategyforrhythmmanagementhybridtherapyforpatientswhoconvertfromatrialfibrillationtoflutteronantiarrhythmicdrugs AT waldoalbertl revisitinganunderrecognizedstrategyforrhythmmanagementhybridtherapyforpatientswhoconvertfromatrialfibrillationtoflutteronantiarrhythmicdrugs |