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Lifespan of long‐lived growth hormone receptor knockout mice was not normalized by housing at 30°C since weaning

Growth hormone receptor knockout (GHRKO) mice are remarkably long‐lived and have improved glucose homeostasis along with altered energy metabolism which manifests through decreased respiratory quotient (RQ) and increased oxygen consumption (VO(2)). Short‐term exposure of these animals to increased e...

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Detalles Bibliográficos
Autores principales: Fang, Yimin, McFadden, Samuel, Darcy, Justin, Hascup, Erin R., Hascup, Kevin N., Bartke, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253058/
https://www.ncbi.nlm.nih.gov/pubmed/32110850
http://dx.doi.org/10.1111/acel.13123