Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer

Weight loss and anorexia are common symptoms in cancer patients that occur prior to initiation of cancer therapy. Inflammation in the brain is a driver of these symptoms, yet cellular sources of neuroinflammation during malignancy are unknown. In a mouse model of pancreatic ductal adenocarcinoma (PD...

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Detalles Bibliográficos
Autores principales: Burfeind, Kevin G, Zhu, Xinxia, Norgard, Mason A, Levasseur, Peter R, Huisman, Christian, Buenafe, Abigail C, Olson, Brennan, Michaelis, Katherine A, Torres, Eileen RS, Jeng, Sophia, McWeeney, Shannon, Raber, Jacob, Marks, Daniel L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253193/
https://www.ncbi.nlm.nih.gov/pubmed/32391790
http://dx.doi.org/10.7554/eLife.54095

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