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Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification
A surgical team from Interplast-Germany removed 387 keloids in 302 patients during 4 visits to Goma, Democratic Republic of the Congo, from 2015-2018. Preoperative and postoperative photographs and a thorough anamnesis of keloids were done for all patients. In addition, 18 selected biopsies from 4 t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer Health
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253266/ https://www.ncbi.nlm.nih.gov/pubmed/32537319 http://dx.doi.org/10.1097/GOX.0000000000002582 |
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author | Lemperle, Gottfried Schierle, Johannes Kitoga, Kakubindi Eric Kassem-Trautmann, Katja Sachs, Christoph Dimmler, Arno |
author_facet | Lemperle, Gottfried Schierle, Johannes Kitoga, Kakubindi Eric Kassem-Trautmann, Katja Sachs, Christoph Dimmler, Arno |
author_sort | Lemperle, Gottfried |
collection | PubMed |
description | A surgical team from Interplast-Germany removed 387 keloids in 302 patients during 4 visits to Goma, Democratic Republic of the Congo, from 2015-2018. Preoperative and postoperative photographs and a thorough anamnesis of keloids were done for all patients. In addition, 18 selected biopsies from 4 types of keloids were histologically examined in Germany. METHODS: Treatment options were tested and keloid recurrence rates were compared with data from questionnaires, photographs, and histology. RESULTS: Keloids were classified accordingly as follows: (1) fresh nodular (continuously growing) keloids had a 30% recurrence rate after surgery: no common adjuvant therapy but triamcinolone acetonide (TAC) injections on onset, only; (a) earlobe keloids had the lowest recurrence rate after complete excision with negative resection margins; (2) superficial spreading (or butterfly) keloids were treated with TAC injections only; (3) mature (nongrowing or burned-out) keloids had also a low recurrence rate of 4.5%, which were then treated with TAC on onset, only; and (4) multiple keloids comprise various types in different stages. CONCLUSIONS: According to this classification, about 50% of keloids may be removed surgically without risk of recurrence in the examined patient population in Africa, where only TAC injections, but no radiation, are available. Adjuvant TAC or radiation should be started at the onset of recurrence and not generally. |
format | Online Article Text |
id | pubmed-7253266 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-72532662020-06-11 Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification Lemperle, Gottfried Schierle, Johannes Kitoga, Kakubindi Eric Kassem-Trautmann, Katja Sachs, Christoph Dimmler, Arno Plast Reconstr Surg Glob Open Original Articles A surgical team from Interplast-Germany removed 387 keloids in 302 patients during 4 visits to Goma, Democratic Republic of the Congo, from 2015-2018. Preoperative and postoperative photographs and a thorough anamnesis of keloids were done for all patients. In addition, 18 selected biopsies from 4 types of keloids were histologically examined in Germany. METHODS: Treatment options were tested and keloid recurrence rates were compared with data from questionnaires, photographs, and histology. RESULTS: Keloids were classified accordingly as follows: (1) fresh nodular (continuously growing) keloids had a 30% recurrence rate after surgery: no common adjuvant therapy but triamcinolone acetonide (TAC) injections on onset, only; (a) earlobe keloids had the lowest recurrence rate after complete excision with negative resection margins; (2) superficial spreading (or butterfly) keloids were treated with TAC injections only; (3) mature (nongrowing or burned-out) keloids had also a low recurrence rate of 4.5%, which were then treated with TAC on onset, only; and (4) multiple keloids comprise various types in different stages. CONCLUSIONS: According to this classification, about 50% of keloids may be removed surgically without risk of recurrence in the examined patient population in Africa, where only TAC injections, but no radiation, are available. Adjuvant TAC or radiation should be started at the onset of recurrence and not generally. Wolters Kluwer Health 2020-03-27 /pmc/articles/PMC7253266/ /pubmed/32537319 http://dx.doi.org/10.1097/GOX.0000000000002582 Text en Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Original Articles Lemperle, Gottfried Schierle, Johannes Kitoga, Kakubindi Eric Kassem-Trautmann, Katja Sachs, Christoph Dimmler, Arno Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification |
title | Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification |
title_full | Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification |
title_fullStr | Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification |
title_full_unstemmed | Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification |
title_short | Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification |
title_sort | keloids: which types can be excised without risk of recurrence? a new clinical classification |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253266/ https://www.ncbi.nlm.nih.gov/pubmed/32537319 http://dx.doi.org/10.1097/GOX.0000000000002582 |
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