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Predicting Phenotypic Polymyxin Resistance in Klebsiella pneumoniae through Machine Learning Analysis of Genomic Data
Polymyxins are used as treatments of last resort for Gram-negative bacterial infections. Their increased use has led to concerns about emerging polymyxin resistance (PR). Phenotypic polymyxin susceptibility testing is resource intensive and difficult to perform accurately. The complex polygenic natu...
Autores principales: | Macesic, Nenad, Bear Don’t Walk, Oliver J., Pe’er, Itsik, Tatonetti, Nicholas P., Peleg, Anton Y., Uhlemann, Anne-Catrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253370/ https://www.ncbi.nlm.nih.gov/pubmed/32457240 http://dx.doi.org/10.1128/mSystems.00656-19 |
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