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Predicting Phenotypic Polymyxin Resistance in Klebsiella pneumoniae through Machine Learning Analysis of Genomic Data

Polymyxins are used as treatments of last resort for Gram-negative bacterial infections. Their increased use has led to concerns about emerging polymyxin resistance (PR). Phenotypic polymyxin susceptibility testing is resource intensive and difficult to perform accurately. The complex polygenic natu...

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Detalles Bibliográficos
Autores principales: Macesic, Nenad, Bear Don’t Walk, Oliver J., Pe’er, Itsik, Tatonetti, Nicholas P., Peleg, Anton Y., Uhlemann, Anne-Catrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253370/
https://www.ncbi.nlm.nih.gov/pubmed/32457240
http://dx.doi.org/10.1128/mSystems.00656-19

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