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Muscarinic Toxin 7 Signals Via Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration
Mitochondrial dysfunction is implicated in a variety of neurodegenerative diseases of the nervous system. Peroxisome proliferator–activated receptor-γ coactivator-1α (PGC-1α) is a regulator of mitochondrial function in multiple cell types. In sensory neurons, AMP-activated protein kinase (AMPK) augm...
Autores principales: | Saleh, Ali, Sabbir, Mohammad Golam, Aghanoori, Mohamad-Reza, Smith, Darrell R., Roy Chowdhury, Subir K., Tessler, Lori, Brown, Jennifer, Gedarevich, Eva, Kassahun, Markos Z., Frizzi, Katie, Calcutt, Nigel A., Fernyhough, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253379/ https://www.ncbi.nlm.nih.gov/pubmed/32198698 http://dx.doi.org/10.1007/s12035-020-01900-x |
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