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Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis

Myocardial ischemia/reperfusion (MI/R) triggers a complicated chain of inflammatory reactions. Dexmedetomidine (Dex) has been reported to be important in myocardial disorders. We evaluated the role of Dex in MI/R injury via the silent information regulator factor 2-related enzyme 1 (SIRT1)/mammalian...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiong, Li, Yongxing, Wang, Yong, Zhuang, Yuerong, Ren, Xiaojie, Yang, Kai, Ma, Wuhua, Zhong, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Cardiovascular System & Vascular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253405/ https://www.ncbi.nlm.nih.gov/pubmed/32406910 http://dx.doi.org/10.1042/BSR20194030

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