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Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer’s Disease

The imbalance in sphingolipid signaling may be critically linked to the upstream events in the neurodegenerative cascade of Alzheimer’s disease (AD). We analyzed the influence of mutant (V717I) amyloid β precursor protein (AβPP) transgene on sphingolipid metabolism enzymes in mouse hippocampus. At 3...

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Detalles Bibliográficos
Autores principales:	Jęśko, Henryk, Wencel, Przemysław L., Wójtowicz, Sylwia, Strosznajder, Joanna, Lukiw, Walter J., Strosznajder, Robert P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253528/ https://www.ncbi.nlm.nih.gov/pubmed/32356173 http://dx.doi.org/10.1007/s12035-020-01908-3

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