Cargando…
Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy
A 64-year-old man with a past medical history of liver transplantation on chronic immunosuppressive therapy presented with gradual worsening of vision over 2 months in his right eye. His recent history of Aspergillus and Nocardia pneumonia with positive bronchoalveolar lavage, in concert with vitrit...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253545/ https://www.ncbi.nlm.nih.gov/pubmed/32462470 http://dx.doi.org/10.1186/s12348-020-00205-3 |
_version_ | 1783539355344699392 |
---|---|
author | Hojjatie, Sara L. Salek, Sherveen S. Pearce, William A. Wells, Jill R. Yeh, Steven |
author_facet | Hojjatie, Sara L. Salek, Sherveen S. Pearce, William A. Wells, Jill R. Yeh, Steven |
author_sort | Hojjatie, Sara L. |
collection | PubMed |
description | A 64-year-old man with a past medical history of liver transplantation on chronic immunosuppressive therapy presented with gradual worsening of vision over 2 months in his right eye. His recent history of Aspergillus and Nocardia pneumonia with positive bronchoalveolar lavage, in concert with vitritis and subretinal abscess, were concerning for endogenous endophthalmitis. A sputum culture and transbronchial lung biopsy stains grew Nocardia farcinica although aqueous humor sampling was negative. He was treated with four serial amikacin intravitreal injections over the course of 4 weeks. Pars plana vitrectomy for worsening macular traction and subsequent cataract surgery resulted in significant clinical and anatomic improvement of vision to 20/60 and consolidation of the subretinal abscess. |
format | Online Article Text |
id | pubmed-7253545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-72535452020-06-08 Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy Hojjatie, Sara L. Salek, Sherveen S. Pearce, William A. Wells, Jill R. Yeh, Steven J Ophthalmic Inflamm Infect Brief Report A 64-year-old man with a past medical history of liver transplantation on chronic immunosuppressive therapy presented with gradual worsening of vision over 2 months in his right eye. His recent history of Aspergillus and Nocardia pneumonia with positive bronchoalveolar lavage, in concert with vitritis and subretinal abscess, were concerning for endogenous endophthalmitis. A sputum culture and transbronchial lung biopsy stains grew Nocardia farcinica although aqueous humor sampling was negative. He was treated with four serial amikacin intravitreal injections over the course of 4 weeks. Pars plana vitrectomy for worsening macular traction and subsequent cataract surgery resulted in significant clinical and anatomic improvement of vision to 20/60 and consolidation of the subretinal abscess. Springer Berlin Heidelberg 2020-05-27 /pmc/articles/PMC7253545/ /pubmed/32462470 http://dx.doi.org/10.1186/s12348-020-00205-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Brief Report Hojjatie, Sara L. Salek, Sherveen S. Pearce, William A. Wells, Jill R. Yeh, Steven Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy |
title | Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy |
title_full | Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy |
title_fullStr | Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy |
title_full_unstemmed | Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy |
title_short | Treatment of presumed Nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy |
title_sort | treatment of presumed nocardia endophthalmitis and subretinal abscess with serial intravitreal amikacin injections and pars plana vitrectomy |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253545/ https://www.ncbi.nlm.nih.gov/pubmed/32462470 http://dx.doi.org/10.1186/s12348-020-00205-3 |
work_keys_str_mv | AT hojjatiesaral treatmentofpresumednocardiaendophthalmitisandsubretinalabscesswithserialintravitrealamikacininjectionsandparsplanavitrectomy AT saleksherveens treatmentofpresumednocardiaendophthalmitisandsubretinalabscesswithserialintravitrealamikacininjectionsandparsplanavitrectomy AT pearcewilliama treatmentofpresumednocardiaendophthalmitisandsubretinalabscesswithserialintravitrealamikacininjectionsandparsplanavitrectomy AT wellsjillr treatmentofpresumednocardiaendophthalmitisandsubretinalabscesswithserialintravitrealamikacininjectionsandparsplanavitrectomy AT yehsteven treatmentofpresumednocardiaendophthalmitisandsubretinalabscesswithserialintravitrealamikacininjectionsandparsplanavitrectomy |