Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus

In humans and experimental animals, the administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight. To gain further insights into the mechanism(s) underlying its satiety effect, we: (i) evaluated the CNTF-dependent activation of the Janus kinase 2 (JAK2) and signal tran...

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Detalles Bibliográficos
Autores principales: Venema, Wiebe, Severi, Ilenia, Perugini, Jessica, Di Mercurio, Eleonora, Mainardi, Marco, Maffei, Margherita, Cinti, Saverio, Giordano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253709/
https://www.ncbi.nlm.nih.gov/pubmed/32528252
http://dx.doi.org/10.3389/fncel.2020.00140

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