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Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer
Lung cancer is one of the leading causes of cancer-related deaths in the United States. A major hurdle for improved therapies is immune suppression mediated by the tumor and its microenvironment. The lung tumor microenvironment (TME) contains large numbers of tumor-associated macrophages (TAMs), whi...
Autores principales: | Geraghty, Terese, Rajagopalan, Anugraha, Aslam, Rabail, Pohlman, Alexander, Venkatesh, Ishwarya, Zloza, Andrew, Cimbaluk, David, DeNardo, David G., Gupta, Vineet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253726/ https://www.ncbi.nlm.nih.gov/pubmed/32528880 http://dx.doi.org/10.3389/fonc.2020.00748 |
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