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Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic

The world is witnessing tumultuous times as major economic powers including the US, UK, Russia, India, and most of Europe continue to be in a state of lockdown. The worst-hit sectors due to this lockdown are sales, production (manufacturing), transport (aerospace and automotive) and tourism. Lockdow...

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Autores principales: Goel, Saurav, Hawi, Sara, Goel, Gaurav, Thakur, Vijay Kumar, Agrawal, Anupam, Hoskins, Clare, Pearce, Oliver, Hussain, Tanvir, Upadhyaya, Hari M., Cross, Graham, Barber, Asa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254035/
https://www.ncbi.nlm.nih.gov/pubmed/32835154
http://dx.doi.org/10.1016/j.mtchem.2020.100300
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author Goel, Saurav
Hawi, Sara
Goel, Gaurav
Thakur, Vijay Kumar
Agrawal, Anupam
Hoskins, Clare
Pearce, Oliver
Hussain, Tanvir
Upadhyaya, Hari M.
Cross, Graham
Barber, Asa H.
author_facet Goel, Saurav
Hawi, Sara
Goel, Gaurav
Thakur, Vijay Kumar
Agrawal, Anupam
Hoskins, Clare
Pearce, Oliver
Hussain, Tanvir
Upadhyaya, Hari M.
Cross, Graham
Barber, Asa H.
author_sort Goel, Saurav
collection PubMed
description The world is witnessing tumultuous times as major economic powers including the US, UK, Russia, India, and most of Europe continue to be in a state of lockdown. The worst-hit sectors due to this lockdown are sales, production (manufacturing), transport (aerospace and automotive) and tourism. Lockdowns became necessary as a preventive measure to avoid the spread of the contagious and infectious “Coronavirus Disease 2019” (COVID-19). This newly identified disease is caused by a new strain of the virus being referred to as Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2; formerly called 2019-nCoV). We review the current medical and manufacturing response to COVID-19, including advances in instrumentation, sensing, use of lasers, fumigation chambers and development of novel tools such as lab-on-the-chip using combinatorial additive and subtractive manufacturing techniques and use of molecular modelling and molecular docking in drug and vaccine discovery. We also offer perspectives on future considerations on climate change, outsourced versus indigenous manufacturing, automation, and antimicrobial resistance. Overall, this paper attempts to identify key areas where manufacturing can be employed to address societal challenges such as COVID-19.
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spelling pubmed-72540352020-05-28 Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic Goel, Saurav Hawi, Sara Goel, Gaurav Thakur, Vijay Kumar Agrawal, Anupam Hoskins, Clare Pearce, Oliver Hussain, Tanvir Upadhyaya, Hari M. Cross, Graham Barber, Asa H. Mater Today Chem Article The world is witnessing tumultuous times as major economic powers including the US, UK, Russia, India, and most of Europe continue to be in a state of lockdown. The worst-hit sectors due to this lockdown are sales, production (manufacturing), transport (aerospace and automotive) and tourism. Lockdowns became necessary as a preventive measure to avoid the spread of the contagious and infectious “Coronavirus Disease 2019” (COVID-19). This newly identified disease is caused by a new strain of the virus being referred to as Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2; formerly called 2019-nCoV). We review the current medical and manufacturing response to COVID-19, including advances in instrumentation, sensing, use of lasers, fumigation chambers and development of novel tools such as lab-on-the-chip using combinatorial additive and subtractive manufacturing techniques and use of molecular modelling and molecular docking in drug and vaccine discovery. We also offer perspectives on future considerations on climate change, outsourced versus indigenous manufacturing, automation, and antimicrobial resistance. Overall, this paper attempts to identify key areas where manufacturing can be employed to address societal challenges such as COVID-19. The Authors. Published by Elsevier Ltd. 2020-09 2020-05-28 /pmc/articles/PMC7254035/ /pubmed/32835154 http://dx.doi.org/10.1016/j.mtchem.2020.100300 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Goel, Saurav
Hawi, Sara
Goel, Gaurav
Thakur, Vijay Kumar
Agrawal, Anupam
Hoskins, Clare
Pearce, Oliver
Hussain, Tanvir
Upadhyaya, Hari M.
Cross, Graham
Barber, Asa H.
Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic
title Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic
title_full Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic
title_fullStr Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic
title_full_unstemmed Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic
title_short Resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic
title_sort resilient and agile engineering solutions to address societal challenges such as coronavirus pandemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254035/
https://www.ncbi.nlm.nih.gov/pubmed/32835154
http://dx.doi.org/10.1016/j.mtchem.2020.100300
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