Cargando…

Apoptotic Cell–Directed Resolution of Lung Inflammation Requires Myeloid αv Integrin–Mediated Induction of Regulatory T Lymphocytes

Intratracheal instillation of apoptotic cells enhances resolution of experimental lung inflammation by incompletely understood mechanisms. We report that this intervention induces functional regulatory T lymphocytes (Tregs) in mouse lung experimentally inflamed by intratracheal administration of lip...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ailiang, Lacy-Hulbert, Adam, Anderton, Stephen, Haslett, Christopher, Savill, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Investigative Pathology 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254048/ https://www.ncbi.nlm.nih.gov/pubmed/32201264 http://dx.doi.org/10.1016/j.ajpath.2020.02.010

Ejemplares similares

Apoptotic cells induce CD103 expression and immunoregulatory function in myeloid dendritic cell precursors through integrin α(v) and TGF-β activation
por: Zhang, Ailiang, et al.
Publicado: (2020)

A Context-Dependent Role for αv Integrins in Regulatory T Cell Accumulation at Sites of Inflammation
por: Mair, Iris, et al.
Publicado: (2018)

Phagocytosis of Apoptotic Cells in Resolution of Inflammation
por: Kourtzelis, Ioannis, et al.
Publicado: (2020)

Persistence of apoptotic cells without autoimmune disease or inflammation in CD14(−/−) mice
por: Devitt, Andrew, et al.
Publicado: (2004)

αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells
por: Acharya, Mridu, et al.
Publicado: (2016)

Relevance of granulocyte apoptosis to resolution of inflammation at the respiratory mucosa
por: Leitch, A E, et al.
Publicado: (2008)

Regulation of Apoptotic Cell Clearance During Resolution of Inflammation
por: Arienti, Simone, et al.
Publicado: (2019)

The astrocyte-expressed integrin αvβ8 governs blood vessel sprouting in the developing retina
por: Hirota, Shinya, et al.
Publicado: (2011)

Myeloid Trem2 Dynamically Regulates the Induction and Resolution of Hepatic Ischemia-Reperfusion Injury Inflammation
por: Han, Sheng, et al.
Publicado: (2023)

Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary
por: Meehan, Tracy L., et al.
Publicado: (2015)

Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis
por: Scatizzi, John C, et al.
Publicado: (2007)

Integrin α PAT-2/CDC-42 Signaling Is Required for Muscle-Mediated Clearance of Apoptotic Cells in Caenorhabditis elegans
por: Hsieh, Hsiao-Han, et al.
Publicado: (2012)

Inflammation-induced effector CD4(+) T cell interstitial migration is alpha-(v) integrin dependent
por: Overstreet, Michael G., et al.
Publicado: (2013)

Induction of Eosinophil Apoptosis by the Cyclin-Dependent Kinase Inhibitor AT7519 Promotes the Resolution of Eosinophil-Dominant Allergic Inflammation
por: Alessandri, Ana L., et al.
Publicado: (2011)

Modulation of Neutrophil Apoptosis and the Resolution of Inflammation through β(2) Integrins
por: El Kebir, Driss, et al.
Publicado: (2013)

β2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune Encephalomyelitis
por: Bednarczyk, Monika, et al.
Publicado: (2022)

Apoptotic Cell Clearance and Its Role in the Origin and Resolution of Chronic Inflammation
por: Muñoz, Luis Enrique, et al.
Publicado: (2015)

Lipoxins and Annexin-1: Resolution of Inflammation and Regulation of Phagocytosis of Apoptotic Cells
por: Scannell, Michael, et al.
Publicado: (2006)

Inflammatory Th17 Cells Express Integrin α(v)β(3) for Pathogenic Function
por: Du, Fang, et al.
Publicado: (2016)

Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis
por: Khurana, Satish, et al.
Publicado: (2016)

Heat Shock Proteins and the Resolution of Inflammation by Lymphocytes
por: Hirsh, Mark I., et al.
Publicado: (2007)

Inflammation-associated genes: risks and benefits to Foxp3(+) regulatory T-cell function
por: O’Connor, Richard A, et al.
Publicado: (2015)

The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver
por: Biswas, Atreyi, et al.
Publicado: (2020)

β2 Integrin Regulation of Neutrophil Functional Plasticity and Fate in the Resolution of Inflammation
por: Sekheri, Meriem, et al.
Publicado: (2021)

Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration
por: McHugh, Brian J., et al.
Publicado: (2012)

Induction of Inflammation by West Nile virus Capsid through the Caspase-9 Apoptotic Pathway
por: Yang, Joo-Sung, et al.
Publicado: (2002)

Regulatory T cells in inflammation and resolution of acute lung injury
por: Wang, Linlin, et al.
Publicado: (2022)

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
por: Takahashi, Kazuya, et al.
Publicado: (2005)

Apoptotic DNase network: Mutual induction and cooperation among apoptotic endonucleases
por: Basnakian, Alexei G., et al.
Publicado: (2021)

New Insights into the Structural Requirements of Isatin-Derived Pro-Apoptotic Agents against Acute Myeloid Leukemia
por: Hamdy, Ahmed K., et al.
Publicado: (2022)

Smooth muscle α(v) integrins regulate vascular fibrosis via CD109 downregulation of TGF-β signalling
por: Li, Zhenlin, et al.
Publicado: (2023)

Distinct Costimulatory Molecules Are Required for the Induction of Effector and Memory Cytotoxic T Lymphocytes
por: Liu, Yang, et al.
Publicado: (1997)

Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution
por: Bao, Lili, et al.
Publicado: (2021)

Characterization of the Effects of Cross-Linking of Macrophage CD44 Associated with Increased Phagocytosis of Apoptotic PMN
por: Hart, Simon P., et al.
Publicado: (2012)

PKA regulatory IIα subunit is essential for PGD(2)-mediated resolution of inflammation
por: Kong, Deping, et al.
Publicado: (2016)

Targeting Apoptotic Pathways in Acute Myeloid Leukaemia
por: Sillar, Jonathan R., et al.
Publicado: (2019)

Loss of Epithelial p53 and αv Integrin Cooperate through Akt to Induce Squamous Cell Carcinoma yet Prevent Remodeling of the Tumor Microenvironment
por: Savar, Aaron, et al.
Publicado: (2014)

Myeloid expression of the anti-apoptotic protein Mcl1 is required in anti-myeloperoxidase vasculitis but myeloperoxidase inhibition is not protective
por: Florez-Barros, Fernanda, et al.
Publicado: (2023)

Induction of eosinophil apoptosis by hydrogen peroxide promotes the resolution of allergic inflammation
por: Reis, A C, et al.
Publicado: (2015)

Adhesion Molecule–dependent Mechanisms Regulate the Rate of Macrophage Clearance During the Resolution of Peritoneal Inflammation
por: Bellingan, Geoffrey John, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_kp1k30s3qn18rjln15984qjab4