Cargando…

Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019

Some patients with coronavirus disease 2019 (COVID-19) show abnormal changes in laboratory myocardial injury markers, suggesting that patients with myocardial injury have a higher mortality rate than those without myocardial injury. This article reviews the possible mechanism of myocardial injury in...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Lin, Zhou, Qi, Xu, Jiancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254078/
https://www.ncbi.nlm.nih.gov/pubmed/32596365
http://dx.doi.org/10.1155/2020/7413673
_version_ 1783539459896115200
author Li, Lin
Zhou, Qi
Xu, Jiancheng
author_facet Li, Lin
Zhou, Qi
Xu, Jiancheng
author_sort Li, Lin
collection PubMed
description Some patients with coronavirus disease 2019 (COVID-19) show abnormal changes in laboratory myocardial injury markers, suggesting that patients with myocardial injury have a higher mortality rate than those without myocardial injury. This article reviews the possible mechanism of myocardial injury in patients with COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the patients with COVID-19 in aspects of direct infection of myocardial injury, specific binding to functional receptors on cardiomyocytes, and immune-mediated myocardial injury. During hospitalization, the monitoring of laboratory myocardial injury markers in patients of COVID-19 should be strengthened.
format Online
Article
Text
id pubmed-7254078
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-72540782020-06-27 Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019 Li, Lin Zhou, Qi Xu, Jiancheng Biomed Res Int Review Article Some patients with coronavirus disease 2019 (COVID-19) show abnormal changes in laboratory myocardial injury markers, suggesting that patients with myocardial injury have a higher mortality rate than those without myocardial injury. This article reviews the possible mechanism of myocardial injury in patients with COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the patients with COVID-19 in aspects of direct infection of myocardial injury, specific binding to functional receptors on cardiomyocytes, and immune-mediated myocardial injury. During hospitalization, the monitoring of laboratory myocardial injury markers in patients of COVID-19 should be strengthened. Hindawi 2020-05-26 /pmc/articles/PMC7254078/ /pubmed/32596365 http://dx.doi.org/10.1155/2020/7413673 Text en Copyright © 2020 Lin Li et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Li, Lin
Zhou, Qi
Xu, Jiancheng
Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019
title Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019
title_full Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019
title_fullStr Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019
title_full_unstemmed Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019
title_short Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019
title_sort changes of laboratory cardiac markers and mechanisms of cardiac injury in coronavirus disease 2019
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254078/
https://www.ncbi.nlm.nih.gov/pubmed/32596365
http://dx.doi.org/10.1155/2020/7413673
work_keys_str_mv AT lilin changesoflaboratorycardiacmarkersandmechanismsofcardiacinjuryincoronavirusdisease2019
AT zhouqi changesoflaboratorycardiacmarkersandmechanismsofcardiacinjuryincoronavirusdisease2019
AT xujiancheng changesoflaboratorycardiacmarkersandmechanismsofcardiacinjuryincoronavirusdisease2019