Cargando…
Histiocyte predominant myocarditis resulting from the addition of interferon gamma to cyclophosphamide-based lymphodepletion for adoptive cellular therapy
BACKGROUND: Adoptive cellular therapy (ACT) is a promising treatment for synovial sarcoma (SS) with reported response rates of over 50%. However, more work is needed to obtain deeper and more durable responses. SS has a ‘cold’ tumor immune microenvironment with low levels of major histocompatibility...
Autores principales: | Schroeder, Brett A, Black, Ralph Graeme, Spadinger, Sydney, Zhang, Shihong, Kohli, Karan, Cao, Jianhong, Mantilla, Jose G, Conrad, Ernest U, Riddell, Stanley R, Jones, Robin L, Yee, Cassian, Pollack, Seth M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254118/ https://www.ncbi.nlm.nih.gov/pubmed/32269142 http://dx.doi.org/10.1136/jitc-2019-000247 |
Ejemplares similares
-
Bendamustine vs. fludarabine/cyclophosphamide lymphodepletion prior to BCMA CAR-T cell therapy in multiple myeloma
por: Sidana, Surbhi, et al.
Publicado: (2023) -
IL-15 mediated expansion of rare durable memory T cells following adoptive cellular therapy
por: Kohli, Karan, et al.
Publicado: (2021) -
Comparison of non-myeloablative lymphodepleting preconditioning regimens in patients undergoing adoptive T cell therapy
por: Nissani, Abraham, et al.
Publicado: (2021) -
Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic melanoma
por: Saberian, Chantal, et al.
Publicado: (2021) -
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8(+) T cells
por: Gattinoni, Luca, et al.
Publicado: (2005)