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Vaccine efficacy against primary and metastatic cancer with in vitro-generated CD103(+) conventional dendritic cells

BACKGROUND: Type 1 conventional dendritic cells (cDC1s) possess efficient antigen presentation and cross-presentation activity, as well as potent T cell priming ability. Tissue-resident cDC1s (CD103(+) cDC1s in mice, CD141(+) cDC1s in humans) are linked with improved tumor control, yet the efficacy...

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Detalles Bibliográficos
Autores principales:	Zhou, Yifan, Slone, Natalie, Chrisikos, Taylor T, Kyrysyuk, Oleksandr, Babcock, Rachel L, Medik, Yusra B, Li, Haiyan S, Kleinerman, Eugenie S, Watowich, Stephanie S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254126/ https://www.ncbi.nlm.nih.gov/pubmed/32273347 http://dx.doi.org/10.1136/jitc-2019-000474

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