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Anti-aging and anti-tumor effect of FPP® supplementation
The beneficial effect of FPP(®) as antioxidant is known. Here we summarize recent data supporting future implementation of FPP(®) in tumor treatment and in controlling aging at the molecular level. We first showed that oral FPP(®) is able to control tumor growth and with inducing a potent and system...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254416/ https://www.ncbi.nlm.nih.gov/pubmed/32499898 http://dx.doi.org/10.4081/ejtm.2019.8905 |
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author | Logozzi, Mariantonia Di Raimo, Rossella Mizzoni, Davide Fais, Stefano |
author_facet | Logozzi, Mariantonia Di Raimo, Rossella Mizzoni, Davide Fais, Stefano |
author_sort | Logozzi, Mariantonia |
collection | PubMed |
description | The beneficial effect of FPP(®) as antioxidant is known. Here we summarize recent data supporting future implementation of FPP(®) in tumor treatment and in controlling aging at the molecular level. We first showed that oral FPP(®) is able to control tumor growth and with inducing a potent and systemic anti-oxidant reaction (i.e. reduced ROS and increased GSH and SOD-1). Then we showed that FPP(®) is able to markedly increase the body anti-oxidant reaction together with increasing both telomerase activity in the blood and the telomeres length in bone marrow and ovary of treated mice as compared to the untreated mice. |
format | Online Article Text |
id | pubmed-7254416 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-72544162020-06-03 Anti-aging and anti-tumor effect of FPP® supplementation Logozzi, Mariantonia Di Raimo, Rossella Mizzoni, Davide Fais, Stefano Eur J Transl Myol Article The beneficial effect of FPP(®) as antioxidant is known. Here we summarize recent data supporting future implementation of FPP(®) in tumor treatment and in controlling aging at the molecular level. We first showed that oral FPP(®) is able to control tumor growth and with inducing a potent and systemic anti-oxidant reaction (i.e. reduced ROS and increased GSH and SOD-1). Then we showed that FPP(®) is able to markedly increase the body anti-oxidant reaction together with increasing both telomerase activity in the blood and the telomeres length in bone marrow and ovary of treated mice as compared to the untreated mice. PAGEPress Publications, Pavia, Italy 2020-04-01 /pmc/articles/PMC7254416/ /pubmed/32499898 http://dx.doi.org/10.4081/ejtm.2019.8905 Text en http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Article Logozzi, Mariantonia Di Raimo, Rossella Mizzoni, Davide Fais, Stefano Anti-aging and anti-tumor effect of FPP® supplementation |
title | Anti-aging and anti-tumor effect of FPP® supplementation |
title_full | Anti-aging and anti-tumor effect of FPP® supplementation |
title_fullStr | Anti-aging and anti-tumor effect of FPP® supplementation |
title_full_unstemmed | Anti-aging and anti-tumor effect of FPP® supplementation |
title_short | Anti-aging and anti-tumor effect of FPP® supplementation |
title_sort | anti-aging and anti-tumor effect of fpp® supplementation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254416/ https://www.ncbi.nlm.nih.gov/pubmed/32499898 http://dx.doi.org/10.4081/ejtm.2019.8905 |
work_keys_str_mv | AT logozzimariantonia antiagingandantitumoreffectoffppsupplementation AT diraimorossella antiagingandantitumoreffectoffppsupplementation AT mizzonidavide antiagingandantitumoreffectoffppsupplementation AT faisstefano antiagingandantitumoreffectoffppsupplementation |