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Free Solution Assay Signal Modulation in Variable-Stem-Length Hairpin Aptamers

[Image: see text] Interferometric measurements of free solution assays (FSAs) quantify changes in molecular conformation and hydration upon binding. Here, we demonstrate that aptamer probes designed to undergo varying levels of conformational change upon binding produce corresponding variations in F...

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Detalles Bibliográficos
Autores principales:	Kammer, Michael N., Kussrow, Amanda K., Olmsted, Ian R., Jackson, George W., Bornhop, Darryl J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254501/ https://www.ncbi.nlm.nih.gov/pubmed/32478218 http://dx.doi.org/10.1021/acsomega.9b04341

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