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GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation

Neurons and oligodendrocytes communicate to regulate oligodendrocyte development and ensure appropriate axonal myelination. Here, we show that Glycerophosphodiester phosphodiesterase 2 (GDE2) signaling underlies a neuronal pathway that promotes oligodendrocyte maturation through the release of solub...

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Detalles Bibliográficos
Autores principales: Choi, Bo-Ran, Cave, Clinton, Na, Chan Hyun, Sockanathan, Shanthini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254694/
https://www.ncbi.nlm.nih.gov/pubmed/32375055
http://dx.doi.org/10.1016/j.celrep.2020.107540