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Apatinib suppresses tumor progression and enhances cisplatin sensitivity in esophageal cancer via the Akt/β-catenin pathway
BACKGROUND: Esophageal cancer is the sixth leading cause of cancer-related mortality worldwide, which is partially due to limited progress of therapy. Apatinib, an inhibitor of VEGFR2, has a promising antitumor effect on malignancies. However, the underlying mechanism of its antitumor effect on esop...
Autores principales: | Wei, Bin, Wang, Yuanyuan, Wang, Jiawei, Cai, Xiaomin, Xu, Lingyan, Wu, Jingjing, Wang, Ying, Liu, Wen, Gu, Yanhong, Guo, Wenjie, Xu, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254695/ https://www.ncbi.nlm.nih.gov/pubmed/32514243 http://dx.doi.org/10.1186/s12935-020-01290-z |
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