Cargando…

Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis

BACKGROUND: Long intergenic non-protein coding RNA 520 (LINC00520), a novel identified lncRNA, has been shown to modulate the malignant phenotype of tumor cells in some malignant tumors. However, the exact role and molecular mechanism of LINC00520 in malignant melanoma has not been studied. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luan, Wenkang, Ding, Yuting, Yuan, Haitao, Ma, Shaojun, Ruan, Hongru, Wang, Jinlong, Lu, Feng, Bu, Xuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254730/ https://www.ncbi.nlm.nih.gov/pubmed/32466797 http://dx.doi.org/10.1186/s13046-020-01599-7

Ejemplares similares

Long noncoding RNA LINC00518 acts as a competing endogenous RNA to promote the metastasis of malignant melanoma via miR-204-5p/AP1S2 axis
por: Luan, Wenkang, et al.
Publicado: (2019)

miR-204-5p acts as a tumor suppressor by targeting matrix metalloproteinases-9 and B-cell lymphoma-2 in malignant melanoma
por: Luan, Wenkang, et al.
Publicado: (2017)

LINC00520: A Potential Diagnostic and Prognostic Biomarker in Cancer
por: Zhang, Qiudan, et al.
Publicado: (2022)

Exosomal miR-106b-5p derived from melanoma cell promotes primary melanocytes epithelial-mesenchymal transition through targeting EphA4
por: Luan, Wenkang, et al.
Publicado: (2021)

Genetic Deletion of the LINC00520 Homolog in Mouse Aggravates Angiotensin II-Induced Hypertension
por: Tang, Xiaofang, et al.
Publicado: (2023)

Exosomes promote hFOB1.19 proliferation and differentiation via LINC00520
por: Wu, Jin, et al.
Publicado: (2023)

Characterization of lncRNA LINC00520 and functional polymorphisms associated with breast cancer susceptibility in Chinese Han population
por: Guo, Qiaoyun, et al.
Publicado: (2020)

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer
por: Henry, Whitney S., et al.
Publicado: (2016)

LncRNA LINC00520 aggravates cell proliferation and migration in lung adenocarcinoma via a positive feedback loop
por: Huang, Wen, et al.
Publicado: (2021)

LncRNA LINC00520 Predicts Poor Prognosis and Promotes Progression of Lung Cancer by Inhibiting MiR-3175 Expression
por: Xia, Gaowei, et al.
Publicado: (2020)

STAT3-mediated upregulation of LINC00520 contributed to temozolomide chemoresistance in glioblastoma by interacting with RNA-binding protein LIN28B
por: Yuan, Shuai, et al.
Publicado: (2022)

Long non-coding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR-22
por: Luan, Wenkang, et al.
Publicado: (2016)

Novel lncRNA SNHG16 Promotes the Growth and Metastasis of Malignant Melanoma by Regulating miR-205-5p/PAK2 Axis
por: Xia, Yun, et al.
Publicado: (2022)

Long noncoding RNA LINC00520 prevents the progression of cutaneous squamous cell carcinoma through the inactivation of the PI3K/Akt signaling pathway by downregulating EGFR
por: Mei, Xue-Ling, et al.
Publicado: (2019)

LINC00518 Promotes Cell Malignant Behaviors via Influencing EIF4A3-Mediated mRNA Stability of MITF in Melanoma
por: Zhang, Ping, et al.
Publicado: (2022)

Long non‐coding RNA ZEB1‐AS1 promotes colon adenocarcinoma malignant progression via miR‐455‐3p/PAK2 axis
por: Ni, Xin, et al.
Publicado: (2019)

Relevance of the Axis Spermidine/eIF5A for Plant Growth and Development
por: Belda-Palazón, Borja, et al.
Publicado: (2016)

LINC01232 Promotes Metastasis and EMT by Regulating miR-506-5p/PAK1 Axis in Gastric Cancer
por: Chen, Gang, et al.
Publicado: (2022)

eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning
por: Pisareva, Vera P., et al.
Publicado: (2014)

eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning
Publicado: (2021)

Eukaryotic Initiation Factor 5B (eIF5B) Cooperates with eIF1A and eIF5 to Facilitate uORF2-Mediated Repression of ATF4 Translation
por: Ross, Joseph A., et al.
Publicado: (2018)

Long noncoding RNA LINC01426 promotes the progression of lung adenocarcinoma via regulating miRNA-125a-5p/ casein kinase 2 alpha 1 axis
por: Zhu, Xiaoling, et al.
Publicado: (2022)

The MNK1/2-eIF4E Axis as a Potential Therapeutic Target in Melanoma
por: Prabhu, Sathyen A., et al.
Publicado: (2020)

Regulation of Autophagy Via PERK-eIF2α Effectively Relieve the Radiation Myelitis Induced by Iodine-125
por: Yang, Zuozhang, et al.
Publicado: (2013)

Role of EIF5A2, a downstream target of Akt, in promoting melanoma cell invasion
por: Khosravi, S, et al.
Publicado: (2014)

The LINC01119-SOCS5 axis as a critical theranostic in triple-negative breast cancer
por: Tu, Zhenbo, et al.
Publicado: (2021)

Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes
por: Zeman, Jakub, et al.
Publicado: (2019)

Dysregulation of Translation Factors EIF2S1, EIF5A and EIF6 in Intestinal-Type Adenocarcinoma (ITAC)
por: Schatz, Christoph, et al.
Publicado: (2021)

LncRNA OGFRP1 acts as an oncogene in NSCLC via miR-4640-5p/eIF5A axis
por: Liu, Xiaojing, et al.
Publicado: (2021)

eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
por: Jennings, Martin D., et al.
Publicado: (2010)

Long non-coding RNA HOTAIR acts as a competing endogenous RNA to promote malignant melanoma progression by sponging miR-152-3p
por: Luan, Wenkang, et al.
Publicado: (2017)

Role of eIF5A in Mitochondrial Function
por: Barba-Aliaga, Marina, et al.
Publicado: (2022)

LINC00888 promoted tumorigenicity of melanoma via miR-126/CRK signaling axis
por: Lu, Wei, et al.
Publicado: (2018)

LINC00680 and TTN-AS1 Stabilized by EIF4A3 Promoted Malignant Biological Behaviors of Glioblastoma Cells
por: Tang, Wei, et al.
Publicado: (2019)

Regulation of the interactions between human eIF5 and eIF1A by the CK2 kinase
por: Gamble, Nathan, et al.
Publicado: (2022)

LINC00313 promotes the proliferation and inhibits the apoptosis of chondrocytes via regulating miR-525-5p/GDF5 axis
por: He, Wen, et al.
Publicado: (2023)

eIF2B promotes eIF5 dissociation from eIF2•GDP to facilitate guanine nucleotide exchange for translation initiation
por: Jennings, Martin D., et al.
Publicado: (2013)

eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B
por: Kim, Eunah, et al.
Publicado: (2018)

LncRNA LINC00460 promotes the papillary thyroid cancer progression by regulating the LINC00460/miR-485-5p/Raf1 axis
por: Li, Guangjun, et al.
Publicado: (2019)

Linc00961 inhibits the proliferation and invasion of skin melanoma by targeting the miR-367/PTEN axis
por: Mu, Xin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1u1p8t5vt5879aevp27llkvl2a