Epidermal growth factor upregulates expression of MUC5AC via TMEM16A, in chronic rhinosinusitis with nasal polyps

BACKGROUND: Mucus hypersecretion and goblet cell upregulation are common features of chronic rhinosinusitis with nasal polyps (CRSwNP). Although epidermal growth factor (EGF) has been reported to stimulate the expression of MUC5AC, the major macro-molecular constituent of airway mucus, the precise m...

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Detalles Bibliográficos
Autores principales: Jiao, Jian, Zhang, Tao, Zhang, Yu, Li, Jingyun, Wang, Min, Wang, Ming, Li, Ying, Wang, Xiangdong, Zhang, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254766/
https://www.ncbi.nlm.nih.gov/pubmed/32514271
http://dx.doi.org/10.1186/s13223-020-00440-2

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