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Direct Identification of Amyloid Peptide Fragments in Human α-Synuclein Based on Consecutive Hydrophobic Amino Acids

[Image: see text] Formation of amyloid fibrils by misfolding α-synuclein is a characteristic feature of Parkinson’s disease, but the exact molecular mechanism of this process has long been an unresolved mystery. Identification of critical amyloid peptide fragments from α-synuclein may hold the key t...

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Detalles Bibliográficos
Autores principales: Chen, Yongzhu, Peng, Fei, Su, Tao, Yang, Hao, Qiu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254785/
https://www.ncbi.nlm.nih.gov/pubmed/32478258
http://dx.doi.org/10.1021/acsomega.0c00979