SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma

Rationale: Hepatocellular carcinoma (HCC) is one of the leading causes of mortality worldwide. Methyltransferase-like 3 (Mettl3), an RNA N6-methyladenosine (m6A) methyltransferase, has been shown to act as an oncogene in several human cancers. However, the regulatory role of posttranslational modifi...

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Detalles Bibliográficos
Autores principales: Xu, Hongfa, Wang, Hao, Zhao, Wei, Fu, Sirui, Li, Yong, Ni, Wenjun, Xin, Yongjie, Li, Wei, Yang, Chenzi, Bai, Yanyan, Zhan, Meixiao, Lu, Ligong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254988/
https://www.ncbi.nlm.nih.gov/pubmed/32483411
http://dx.doi.org/10.7150/thno.42539

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