Cargando…
Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury
Aims: Cisplatin, an anticancer drug, always leads to nephrotoxicity by causing mitochondrial dysfunction. As a major mechanism for cellular self-degradation, autophagy has been proven to protect against cisplatin-induced acute kidney injury (AKI). Based on the activation of autophagy induced by treh...
Autores principales: | Zhu, Lingling, Yuan, Yujia, Yuan, Longhui, Li, Lan, Liu, Fei, Liu, Jingping, Chen, Younan, Lu, Yanrong, Cheng, Jingqiu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255003/ https://www.ncbi.nlm.nih.gov/pubmed/32483422 http://dx.doi.org/10.7150/thno.44051 |
Ejemplares similares
-
PGC-1α alleviates mitochondrial dysfunction via TFEB-mediated autophagy in cisplatin-induced acute kidney injury
por: Yuan, Longhui, et al.
Publicado: (2021) -
Molecular mechanisms and physiological functions of autophagy in kidney diseases
por: Yang, Jingchao, et al.
Publicado: (2022) -
Phloretin attenuates hyperuricemia‐induced endothelial dysfunction through co‐inhibiting inflammation and GLUT9‐mediated uric acid uptake
por: Liu, Shuyun, et al.
Publicado: (2017) -
LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss
por: Liu, Fei, et al.
Publicado: (2021) -
Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance
por: Zhao, Meng, et al.
Publicado: (2021)