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BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation

EGFR TKI therapy has become a first-line regimen for non-small cell lung cancer (NSCLC) patients with EGRF mutations. However, there are two big challenges against effective therapy--the secondary EGFR mutation-associated TKI resistance and brain metastasis (BMs) of lung cancer. The BMs is a major c...

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Detalles Bibliográficos
Autores principales: Yin, Weimin, Zhao, Yuge, Kang, Xuejia, Zhao, Pengfei, Fu, Xuhong, Mo, Xiaopeng, Wan, Yakun, Huang, Yongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255027/
https://www.ncbi.nlm.nih.gov/pubmed/32483443
http://dx.doi.org/10.7150/thno.42234