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Structure and mechanism of human diacylglycerol O-acyltransferase-1

Diacylglycerol O-acyltransferase-1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans(1). DGAT1 belongs to the superfamily of membrane-bound O-acyltransferases (MBOAT) that are found in all kingdoms of life and involved in acylation of lipids a...

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Detalles Bibliográficos
Autores principales: Wang, Lie, Qian, Hongwu, Nian, Yin, Han, Yimo, Ren, Zhenning, Zhang, Hanzhi, Hu, Liya, Prasad, B. V. Venkataram, Laganowsky, Arthur, Yan, Nieng, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255049/
https://www.ncbi.nlm.nih.gov/pubmed/32433610
http://dx.doi.org/10.1038/s41586-020-2280-2