Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir

• Two cases of Serotonin syndrome (SS) in COVID-19 patients are presented. • Lopinavir/ritonavir (LPV/r) have been widely used during the COVID-19 pandemic. • LPV/r with duloxetine and lithium triggered SS in patient 1. • LPV/r with risperidone, and probably also morphine, triggered SS in patient 2....

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Detalles Bibliográficos
Autores principales: Mas Serrano, Miguel, Pérez-Sánchez, Javier Ricardo, Portela Sánchez, Sofía, De La Casa-Fages, Beatriz, Mato Jimeno, Víctor, Pérez Tamayo, Isabel, Grandas, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255189/
https://www.ncbi.nlm.nih.gov/pubmed/32531579
http://dx.doi.org/10.1016/j.jns.2020.116944
Descripción
Sumario:• Two cases of Serotonin syndrome (SS) in COVID-19 patients are presented. • Lopinavir/ritonavir (LPV/r) have been widely used during the COVID-19 pandemic. • LPV/r with duloxetine and lithium triggered SS in patient 1. • LPV/r with risperidone, and probably also morphine, triggered SS in patient 2. • A Video of patient 2 shows myoclonus and ocular clonus in the context of SS.

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