Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir

• Two cases of Serotonin syndrome (SS) in COVID-19 patients are presented. • Lopinavir/ritonavir (LPV/r) have been widely used during the COVID-19 pandemic. • LPV/r with duloxetine and lithium triggered SS in patient 1. • LPV/r with risperidone, and probably also morphine, triggered SS in patient 2....

Descripción completa

Detalles Bibliográficos
Autores principales: Mas Serrano, Miguel, Pérez-Sánchez, Javier Ricardo, Portela Sánchez, Sofía, De La Casa-Fages, Beatriz, Mato Jimeno, Víctor, Pérez Tamayo, Isabel, Grandas, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255189/
https://www.ncbi.nlm.nih.gov/pubmed/32531579
http://dx.doi.org/10.1016/j.jns.2020.116944
_version_ 1783539684815667200
author Mas Serrano, Miguel
Pérez-Sánchez, Javier Ricardo
Portela Sánchez, Sofía
De La Casa-Fages, Beatriz
Mato Jimeno, Víctor
Pérez Tamayo, Isabel
Grandas, Francisco
author_facet Mas Serrano, Miguel
Pérez-Sánchez, Javier Ricardo
Portela Sánchez, Sofía
De La Casa-Fages, Beatriz
Mato Jimeno, Víctor
Pérez Tamayo, Isabel
Grandas, Francisco
author_sort Mas Serrano, Miguel
collection PubMed
description • Two cases of Serotonin syndrome (SS) in COVID-19 patients are presented. • Lopinavir/ritonavir (LPV/r) have been widely used during the COVID-19 pandemic. • LPV/r with duloxetine and lithium triggered SS in patient 1. • LPV/r with risperidone, and probably also morphine, triggered SS in patient 2. • A Video of patient 2 shows myoclonus and ocular clonus in the context of SS.
format Online
Article
Text
id pubmed-7255189
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-72551892020-05-28 Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir Mas Serrano, Miguel Pérez-Sánchez, Javier Ricardo Portela Sánchez, Sofía De La Casa-Fages, Beatriz Mato Jimeno, Víctor Pérez Tamayo, Isabel Grandas, Francisco J Neurol Sci Article • Two cases of Serotonin syndrome (SS) in COVID-19 patients are presented. • Lopinavir/ritonavir (LPV/r) have been widely used during the COVID-19 pandemic. • LPV/r with duloxetine and lithium triggered SS in patient 1. • LPV/r with risperidone, and probably also morphine, triggered SS in patient 2. • A Video of patient 2 shows myoclonus and ocular clonus in the context of SS. Elsevier B.V. 2020-08-15 2020-05-27 /pmc/articles/PMC7255189/ /pubmed/32531579 http://dx.doi.org/10.1016/j.jns.2020.116944 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Mas Serrano, Miguel
Pérez-Sánchez, Javier Ricardo
Portela Sánchez, Sofía
De La Casa-Fages, Beatriz
Mato Jimeno, Víctor
Pérez Tamayo, Isabel
Grandas, Francisco
Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir
title Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir
title_full Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir
title_fullStr Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir
title_full_unstemmed Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir
title_short Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir
title_sort serotonin syndrome in two covid-19 patients treated with lopinavir/ritonavir
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255189/
https://www.ncbi.nlm.nih.gov/pubmed/32531579
http://dx.doi.org/10.1016/j.jns.2020.116944
work_keys_str_mv AT masserranomiguel serotoninsyndromeintwocovid19patientstreatedwithlopinavirritonavir
AT perezsanchezjavierricardo serotoninsyndromeintwocovid19patientstreatedwithlopinavirritonavir
AT portelasanchezsofia serotoninsyndromeintwocovid19patientstreatedwithlopinavirritonavir
AT delacasafagesbeatriz serotoninsyndromeintwocovid19patientstreatedwithlopinavirritonavir
AT matojimenovictor serotoninsyndromeintwocovid19patientstreatedwithlopinavirritonavir
AT pereztamayoisabel serotoninsyndromeintwocovid19patientstreatedwithlopinavirritonavir
AT grandasfrancisco serotoninsyndromeintwocovid19patientstreatedwithlopinavirritonavir

Ejemplares similares